Professor Vivette Glover is an international expert on the effect of the mother’s emotional state in pregnancy on the development of the fetus and her child. She is professor of perinatal psychobiology at Imperial College London.
She originally studied biochemistry at Oxford and did her PhD at University College London. In 1975 she came to work at Queen Charlotte’s, and developed an interest in biological psychiatry in relation to pregnancy and the postnatal period. In more recent years she has focused especially on the effect of the mother’s mood on fetal development. She has over 400 publications, and is invited to speak, including giving the keynote address, at meetings around the world. She is a special advisor to the Department of Health on the Family Nurse Partnership, which supports teenage mothers, and on antenatal education.
Her first degree was in biochemistry at Oxford University, and she undertook her PhD in neurochemistry at University College London.
Professor Glover has worked at Queen Charlotte's and Chelsea Hospital, London where she became head of the Fetal and Neonatal Stress Research Group. Here she undertook work investigating postnatal depression and was involved in trials to improve symptoms for mothers. In more recent years she has applied her expertise in biological psychiatry to the problems of mothers and babies. Recent projects of interest include studies showing that maternal prenatal stress, depression or anxiety increases the probability for a range of adverse neurodevelopmental outcomes for the child. These include emotional problems, attention deficit/ hyperactivity disorder, conduct disorder, and cognitive impairment. Her group are also studying the biological mechanisms that may underlie such fetal programming. Professor Glover is currently treasurer of the Marcé Society.
Awards and honours:
Professor Glover was awarded the Parent Infant Partnership UK Award for Research in Pregnancy and Infant Mental Health in 2014. She has also been awarded the Marcé Society Medal.
Gitau R, Cameron A, Fisk NM, Glover V. (1998) Fetal exposure to maternal cortisol. Lancet 352, 707–708.
Teixeira J, Fisk N, Glover V. (1999) Association between maternal anxiety in pregnancy and increased uterine artery resistance index: cohort based study. BMJ 318, 153–157.
Taylor, A., Fisk, N.M., Glover, V. (2000) Mode of delivery and subsequent stress response. Lancet 355, 120
Gitau R, Fisk NM, Cameron A, Teixeira J, Glover V. (2001). Fetal HPA stress responses to invasive procedures are independent of maternal responses. J Clin End Met. 86, 104–109
O’Connor TG, Heron J, Golding J, Beveridge M, Glover V (2002) Maternal Antenatal Anxiety and Behavioural Problems in Early Childhood. Brit J Psychiat 180, 502–508
O’Connor, T.G., Heron, J., Golding, J., & Glover, V., and the ALSPAC study team (2003). Maternal Antenatal Anxiety and Behavioural/Emotional Problems in Children: A Test of a Programming Hypothesis. J Child Psychol Psychiat 44,1025–1036
Miller NM, Fisk NM, Modi N, Glover V (2005) Stress responses at birth: determinants of cord arterial cortisol and links with cortisol response in infancy. Bjog; 112(7): 921–6.
Van den Bergh BR, Mulder EJ, Mennes M, Glover V (2005) Antenatal maternal anxiety and stress and the neurobehavioural development of the fetus and child: links and possible mechanisms. A review. Neurosci Biobehav Rev; 29(2): 237–58.
O'Connor TG, Ben-Shlomo Y, Heron J, Golding J, Adams D, Glover V (2005) Prenatal Anxiety Predicts Individual Differences in Cortisol in Pre-Adolescent ChildrenBiol Psychiatry ; 58:211–217.
Glover V, Miles R, Matta S, Modi N, Stevenson J. (2005) Glucocorticoid exposure in preterm babies predicts saliva cortisol response to immunisation at 4 months. Ped Res ; 58(6):1233–1237
Sarkar P, Bergman K, Fisk NM, Glover V.(2006) Maternal anxiety at amniocentesis and plasma cortisol. Prenat Diagn. 26(6):505-9
Talge NM, Neal C, Glover V (2007) Antenatal maternal stress and long-term effects on child neurodevelopment: how and why? J Child Psychol Psychiatry. 48 :245-61
Sarkar P, Bergman K, Fisk NM, O'Connor TG, Glover V (2007) Ontogeny of foetal exposure to maternal cortisol using midtrimester amniotic fluid as a biomarker Clin Endocrinol 66(5) 636-40.
Igosheva N, Taylor PD, Poston L, Glover V. (2007) Prenatal stress in the rat results in increased blood pressure responsiveness to stress and enhanced arterial reactivity to neuropeptide Y in adulthood. J. Physiol. 582 :665-74
O'Connor TG, Caprariello P, Blackmore ER, Gregory AM, Glover V, Fleming P;(2007) ALSPAC Study Team. Prenatal mood disturbance predicts sleep problems in infancy and toddlerhood. Early Hum Dev. l;83(7):451-8.
Bergman K, Sarkar P, O'Connor TG, Modi N, Glover V (2007) Maternal stress during pregnancy predicts cognitive ability and fearfulness in infancy. J. Am. Acad. Child. Adolesc. Psychiatr 46: 1454–1463
Bergman, K., Sarkar, P., Glover, V., & O’Connor, T.G. (2008). Quality of child-parent attachment moderates the impact of antenatal stress on child fearfulness. J Child Psychol Psychiatry. 49:1089–1098
Glover V, Bergman K, Sarkar P, O'Connor TG.(2009) Association between maternal and amniotic fluid cortisol is moderated by maternal anxiety. Psychoneuroendocrinology. 34(3) 430-5
Kammerer M, Marks MN, Pinard C, Taylor A, von Castelberg B, Künzli H, Glover V.(2009) Symptoms associated with the DSM IV diagnosis of depression in pregnancy and post partum. Arch Women's Ment Health. 12(3):135-41.
Taylor A, Glover V, Marks M, Kammerer M (2009) Diurnal pattern of cortisol output in postnatal depression Psychoneuroendocrinology 34(8):1184-8
Glover V, O'Connor TG, O'Donnell K. (2009) Prenatal stress and the programming of the HPA axis. Neurosci Biobehav Rev. 12(6):549-54.
Bergman K, Glover V, Sarkar P, Abbott DH, O'Connor TG.(2010) In utero cortisol and testosterone exposure and fear reactivity in infancy. Horm Behav. ;57(3):306-12.