Nationality

Iranian

Date and place of birth

1990, Alborz, Iran

Education

2010-2014 B.Sc.; Cellular and Molecular Sciences

Islamic Azad University - Tonekabon Branch

2014-2017 M.Sc.; Cellular and Molecular Sciences

Islamic Azad University Tehran Science and Research Branch

Thesis title

Cytotoxic and anticancer effects of ICD-85 (Venom derived peptides) in human breast adenocarcinoma and normal human dermal fibroblasts

From 2017 Ph.D. Student.; Cellular and Molecular Sciences

Islamic Azad University Tehran Science and Research Branch

Affiliations

1. Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.

2. Department of Venomous Animal and Antivenom Production, Razi Vaccine and Serum Research Institute, Agriculture Research Education and Extension Organization (AREEO), Karaj, Iran.

3. Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

4. Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran.

5. Cancer Biology Signaling Pathway Interest Group (CBSPIG), Universal Scientific Education and Research Network (USERN), Tehran, Iran.

Work and Research Experiences

Researcher at Department of Venomous Animal and Antivenom Production, Razi Vaccine and Serum Research Institute, Agriculture Research Education and Extension Organization (AREEO), Karaj, Iran. January 2016 - September 2017.

Researcher at Cancer Research Center, Shohada Tajrish Hospital, Department of Radiation Oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. January 2016 - September 2022.

Founder and managing director of Cancer Biology Signaling Pathway Interest Group (CBSPIG), Universal Scientific Education and Research Network (USERN), Tehran, Iran. December 2020 - Present.

Researcher at Nanotechnology, Agricultural Biotechnology Research Institute of Iran (ABRII), Agricultural Research, Education, and Extension Organization (AREEO), Karaj, Iran. October 2022 - Present.

Poster presentation

1. Investigation of The Effect of ICD-85 (Venom Derived Peptides) on Inhibition of Breast Cancer Cell Line (MCF-7). 16th National Congress of Iranian Biochemistry, August 2016, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

2. Cytotoxic Effect of Black Widow Spider Venom (Latrodectus dahli) on Human Embryonic Kidney Cell Line (HEK-293). 16th National Congress of Iranian Biochemistry, August 2016, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

3. A Comprehensive Bioinformatic Evaluation the NTRK Family as Prognostic Biomarkers in Breast Cancer. 2nd International and 11th National Iranian Conference on Bioinformatics, 28 February - 1 March 2023, Tehran, Iran.

Research Grants

Collaborator at Clinical trial (phase 1) of ICD-85 as an anti-cancer compound in patients with metastatic cancer, Cancer Research Center, Shohada Tajrish Hospital, Department of Radiation Oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran, 2016.

Collaborator at the CD8+ T cell exhaustion mechanisms in chronic hepatitis B infection and immunotherapeutic strategies: a systematic review, Baqiyatallah Research Center for Gastroenterology and Liver Diseases (BRCGL), Baqiyatallah University of Medical Sciences, Tehran, Iran, 2022.

Collaborator at Design and development Helicobacter pylori diagnostic kit based on tetra-ARMs PCR method, Baqiyatallah Research Center for Gastroenterology and Liver Diseases (BRCGL), Baqiyatallah University of Medical Sciences, Tehran, Iran, 2023.

Educational Courses and Certificates

Certificate, Workshop of Systematic Review, Universal Scientific Education and Research Network (USERN), Tehran, Iran, November 2020.

Certificate, Workshop of Meta-analysis, Universal Scientific Education and Research Network (USERN), Tehran, Iran, November 2020.

Certificate, Workshop of scientific writing, Universal Scientific Education and Research Network (USERN), Tehran, Iran, February 2021.

Certificate, Workshop of Publishing Academic Books in Collaboration with International Publishers, Universal Scientific Education and Research Network (USERN), Tehran, Iran, March 2021.

Certificate, Workshop of EndNote, Universal Scientific Education and Research Network (USERN), Tehran, Iran, March 2021.

Certificate, Workshop of Poster Designing, Universal Scientific Education and Research Network (USERN), Tehran, Iran, April 2021.

Certificate, CRISPR Symposium, First International and Third Iranian CRISPR Symposium, Tehran, Iran, April 2021.

Certificate, Workshop of Choosing of the Appropriate Journal, Universal Scientific Education and Research Network (USERN), Tehran, Iran, June 2021.

Certificate, Workshop of Answer to the Comments of the Reviewer, Universal Scientific Education and Research Network (USERN), Tehran, Iran, June 2021.

Certificate, Workshop of SPSS, Universal Scientific Education and Research Network (USERN), Tehran, Iran, June 2021.

Certificate, AIDS Symposium, Organized by Pasteur Institute of Iran, Shahid Chamran University and Iranian Biologists Union, Tehran, Iran, December 2021.

Certificate, Manipulating and Analysing Protein Structure by PyMol Software, International Association of Scientists (IAS), August 2022.

Certificate, Webinar of Accelerating CAR-T cell therapy Research for the Fight Against Cancer, Cyagen Biosciences, London, July 2023.

Journal reviewer

Frontiers in Medicine (Frontiers Media S.A.)

Health Science Reports (Wiley)

Nephro-Urology Monthly (Brieflands)

BMJ Open Gastroenterology (BMJ Publishing Group)

Traditional & Integrative Medicine (Tehran University of Medical Sciences)

Journal of pharmaceutical research international

Published articles

1. Ghanbar Mahmoodi Chalbatani, Hassan Dana, Feridon Memari, Elahe Gharagozlou, Shirin Ashjaei, Peyman Kheirandish Zarandi, et al. Biological function and molecular mechanism of piRNA in cancer. Practical Laboratory Medicine. 2019 Jan 1;13:e00113. IF:1.9

2. Peyman Kheirandish Zarandi, Abbas Zare Mirakabadi, Fattah Sotoodehnejadnematalahi. Cytotoxic and Anticancer Effects of ICD-85 (Venom Derived Peptides) in Human Breast Adenocarcinoma and Normal Human Dermal Fibroblasts. Iranian Journal of Pharmaceutical Research. 2019; 18(1): 232-240. IF:1.6

3. Mohammad Reza Zinatizadeh, Seyed Ali Momeni, Peyman Kheirandish Zarandi, Ghanbar Mahmoodi Chalbatani, Hassan Dana, Hamid Reza Mirzaei, et al. The Role and Function of Ras-association domain family in Cancer: A Review. Genes & diseases. 2019 Dec 1;6(4):378-84. IF:6.8

4. Mohammad Reza Zinatizadeh, Seyed Rouhollah Miri, Peyman Kheirandish Zarandi, Ghanbar Mahmoodi Chalbatani, Catarina Rapôso, Hamid Reza Mirzaei, et al. The Hippo Tumor Suppressor Pathway (YAP/TAZ/TEAD/MST/LATS) and EGFR-RAS-RAF-MEK in cancer metastasis. Genes & Diseases. 2019 Dec 5. IF:6.8

5. Mohammad Reza Zinatizadeh, Abbas Zare Mirakabadi, Peyman Kheirandish Zarandi, Hamid Reza Mirzaei, Farzaneh Parnak, Sholeh Javadi. The Effects of ICD-85 in vivo and in vitro in Treatment of Cancer. Asia Pacific Journal of Medical Toxicology. 2019 Dec 1;8(4):130-5.

6. Mohammad Reza Zinatizadeh, Bettina Schock, Ghanbar Mahmoodi Chalbatani, Peyman Kheirandish Zarandi, Seyed Amir Jalali, Seyed Rouhollah Miri. The Nuclear Factor Kappa B (NF-kB) signaling in cancer development and immune diseases. Genes & Diseases. 2020. https://doi.org/10.1016/j.gendis.2020.06.005 IF:6.8

7. Hassan Dana, Ghanbar Mahmoodi Chalbatani, Elahe Gharagouzloo, Seyed Rouhollah Miri, Fereidoon Memari, Reza Rasoolzadeh, Mohammad Reza Zinatizadeh, Peyman Kheirandish Zarandi, Vahid Marmari. In silico analysis, molecular docking, molecular dynamic, cloning, expression and purification of chimeric protein in colorectal cancer treatment. Drug design, development and therapy. 2020;14:309. IF:4.3

8. Peyman Kheirandish Zarandi, Mohammad Reza Zinatizadeh, Mohammad Hadi Yousefi, Hamid Reza Mirzaei, Mohammad Esmaeil Akbari. An Overview of the Mitogenic RAS Effectors and its Therapeutic Approaches. Paramedical Sciences and Military Health. 2020, 15(1): 50-55.

9. Mohammad Reza Zinatizadeh, Abba Zare Mirakabadi, Hamid Reza Mirzaei, Mohammad Esmaeil Akbari, Peyman Kheirandish Zarandi. Anti-Cancer Effects of Animal Venoms; a Review Study. Health Research Journal. 2020 Jan 10;5(2):96-102.

10. Peyman Kheirandish Zarandi, Mohammad Reza Zinatizadeh, Maryam Zinatizadeh, Mohammad Hadi Yousefi, Nima Rezaei. SARS-CoV-2: From the pathogenesis to potential anti-viral treatments. Biomedicine & Pharmacotherapy. 2021 Feb 2:111352. IF:7.5

11. Mohammad Reza Zinatizadeh, Peyman Kheirandish Zarandi, Maryam Zinatizadeh, Mohammad Hadi Yousefi, Jafar Amani, Nima Rezaei. Efficacy of mRNA, Adenoviral Vector, and Perfusion Protein COVID-19 Vaccines. Biomedicine & Pharmacotherapy. 10 December 2021, 112527. IF:7.5

12. Mohammad Reza Zinatizadeh, Peyman Kheirandish Zarandi, Mahsa Keshavarz-Fathi, Mohammad Hadi Yousefi, Nima Rezaei. The role of ral signaling and post translational modifications (PTMs) of Ras in cancer. Genome Instability & Disease. 17 January 2022.

13. Mohammad Reza Zinatizadeh, Peyman Kheirandish Zarandi, Mohsen Ghiasi, Hamid Kooshki, Mozafar Mohammadi, Jafar Amani, Nima Rezaei. Immunosenescence and inflamm-ageing in COVID-19. Ageing Research Reviews. February 2023. IF:13.1

14. Esmaeil Allahmoradi, Ramtin Mohammadi, Peyman Kheirandish Zarandi, Seyed Moayed Alavian, Mohammad Heiat. The CD8+ T cell exhaustion mechanisms in chronic hepatitis B infection and immunotherapeutic strategies: a systematic review. Expert Review of Clinical Immunology. March 2023. IF:5.1

15. Ramtin Mohammadi, Ali Zareh, Elmira Rabani, Peyman Kheirandish Zarandi, Ahmad Khoncheh, Mohammad Heiat. Expression of Pivotal Long Non-coding RNAs Implicated in Gastric Cancer: A Bioinformatic and Clinical Study. Biochemical Genetics. December 2023. IF:2.4

16. Mohsen Ghiasi, Peyman Kheirandish Zarandi, Abdolreza Dayani, Ali Salimi, Ehsan Shokri. Potential therapeutic effects and nano-based delivery systems of mesenchymal stem cells and their isolated exosomes to alleviate acute respiratory distress syndrome caused by COVID-19. Regenerative Therapy. December 2024. IF:4.3

Translated book

NF-kB-related genetic diseases

The science of stem cells

Honors

Founder and managing director of cancer biology signaling pathway interest group (CBSPIG)

Membership at the Young Researchers and Elite Club

Membership at the National Foundation of Elites

Computer skills

Microsoft Office

SigmaPlot, SPSS

Adobe Illustrator, Inkscape, Autodesk SketchBook

EndNote